Eukaryotic Rieske non-heme iron oxygenases

Rieske oxygenases catalyze difficult-to-carry-out reactions in a chemistry lab. They are non-heme iron enzymes with a 2-His-1-carboxylate mononuclear Fe center. They activate molecular oxygen to catalyze stereospecific cis-dihydroxylation (like in Naphthalene 1,2 deoxygenate) and various other reactions. While Rieske oxygenases have been shown to be present in prokaryotes and many eukaryotes, there are no Rieske oxygenases identified in humans.