WILLIAM CRAMER

Henry Koffler Distinguished Professor of Biological Sciences
765-494-4956
HOCK 325
waclab@purdue.edu

Associated website(s):

Lab , PULSe , Publications

PROFESSIONAL FACULTY RESEARCH

Structure/function of membrane proteins involved in charge translocation and protein import: photosynthetic electron transport and energy transduction; cytochrome complexes; colicins: ion channels, cellular import, receptor function; antibiotic-resistant cytotoxin; structure-function/membrane interactions of Parkinson protein, -synuclein.

BIO

Education/Training

INSTITUTION AND LOCATION

DEGREE

YEAR(s)

FIELD OF STUDY

Massachusetts Institute of Technology

B.S.

1959

Physics

University of Chicago

M.S.

1960

Physics

University of Chicago

Ph.D.

1965

Biophysics

PROFESSIONAL EXPERIENCE

NSF Postdoctoral Fellow, 1965-'67; University of California/San Diego, Department of Biology, Research Associate, 1967-'68; Assistant Professor, Dept. of Biological Sciences, Purdue University, 1968-'73; Associate Professor, 1973-'78; Professor, 1978-; Associate Head, 1984-'86; Henry Koffler Professor, 1995-2000; PI, Biophysics Training Grant, 1995 – 2001, Purdue University, Department of Biological Sciences: Henry Koffler Distinguished Professor, 2001-.

HONORS/AWARDS; Prominent Lectures

National Science Foundation Postdoctoral Fellowship, Univ. California/San Diego 1965-67;

NIH(NIGMS) Research Career Development Award, 1970-75;

Senior Fellow, European Molecular Biology Org., Univ. of Amsterdam, The Netherlands, 1974-75;

Annual Reviews, (1977-2012) five reviews in four different Ann. Rev . areas;

McCoy Award, Purdue University, Achievements in Science, 1988;

Plenary Lectures, International Congress of Photosynthesis, 1989, 2004;

Fellow, Alexander von Humboldt Foundation, 1992;

Fellow, John Simon Guggenheim Foundation, 1992-93;

C.F. Kettering Award, Amer. Soc. Plant Physiology, 1996;

Rosetta Briegel Barton Lecture, University of Oklahoma, 2001;

Maurice Hilleman Lecture, Montana State University, 2004;

Daniel Arnon Lecture, University of California/Berkeley, 2006;

Fellow, Biophysical Society, 2007;

Eminent Scholar Lecture, Oklahoma State University, 2008;

Fellow, American Association for the Advancement of Science, 2017;

Orton K. Stark Distinguished Lectures, Miami University, 2017;

Keynote Awardee, 9 ^th International Conference on Photosynthesis & Hydrogen Energy Research for Sustainability , Hyderabad, India, 2017

Symposium Lecture, 10th International Conference on Photosynthesis, St. Petersburg, Russia, 2019

'Structure-Function of the Cytochrome b6f Complex,' Cytochrome Symposium, American Society of Biological Chemistry, August, 2021

MAJOR RESEARCH INTERESTS

MEMBERSHIPS

AAAS; American Society of Biological Chemistry/Molecular Biology; Biophysical Society.

EXTRAMURAL SERVICE

Grants Panels and Study Sections

NSF-NRC Predoctoral Fellowships in Biochemistry and Biophysics, 1977-79; Panel Chair, 1979
NSF Grants Panel, Biophysics and Biochemistry, 1979-81;
USDA Competitive Grants, 1983, 84
NSF Grants Panel, Cellular Biochemistry, 1989-91
NIHGMS/NIH Study Sections: Physical Biochemistry, 1991-95; Special Emphasis on Biophysics/Biochemistry, 11/04; Biological Chemistry and Macromolecular Biophysics, ‘05; Program Project Grants, 4/05; Roadmap Initiative for Membrane Proteins, 6/05; Biophysics and Biochemistry Fellowships, 2006; RFA, Membrane Proteins, 3/07; NIHGMS “Eureka,” 4/09; Instrumentation, 10/09; NIHGMS, Biochemistry/Biophysics of Membranes, 01/10; Special Emphasis, 01/11; Biochemistry/Biophysics of Membranes, 06/11,10/12-6/16.
Dept. of Energy, DOE/BES Photo- and Biochemistry, Lawrence Berkeley Lab, 07/11; DOE Study Section, 2019.
Editorial Boards (service completed): Arch. Biochem. Biophys ; Photosyn. Res ; J. Bioenerg. Biomembranes , Biochimica Biophysica Acta (Bioenergetics), Biochemical Journal (2003-2006) , Biophysical Journal (1999-2005); Journal of Biological Chemistry , 2002-2007, 2010-2014.
Chair, Gordon Conferences, (i) “Biochemical Aspects of Photosynthesis,”1990; (ii) “Bioenergetics,” 2001.
Biophysical Society: Chair, Bioenergetics Subgroup, 1989-92; Organizing Comm., Biophysical Discussions, 1992-93; Chair, National Mtg., 1996; Council, 1996-00, Executive Council, 2000-02; Editor, “Energy Transduction in Biological Membranes” (ed.), Educational Resources.
FASEB Comm., Ethical Issues in Genetic Res., 1997-99.
Multi-National Student Ph. D. Committee: Univ. of Paris, France; Lund Univ., Sweden.

TEACHING

( A ) Univ. California/San Diego, Undergraduate Cell Biology; ( B ) Purdue University: ( 1 ) graduate Courses in ( a ) Bioenergetics (textbook published); applications to cancer; ( b ) Membrane Proteins; applications to cancer; ( c ) Ethics: Life and Time in Academic Research Labs; ( 2 ) Undergraduate courses, latest, Energy Transduction in Biology & Medicine ; ( a ) Cell Biology, ( b ) Active Transport, ( c ) Biochemistry Laboratory.

Publications

A. Books; Textbook; Educational Resources

Govindjee, J. Barber, W. A. Cramer, J. H. C. Goedheer, J. Lavorel, R. Marcelle, and B. Zilinskas (eds.). 1987. Excitation Energy and Electron Transfer in Photosynthesis . Martinus Nijhoff, Dordrecht, 518 pp.

Cramer, W. A., and D. B. Knaff. 1991. Energy Transduction in Biological Membranes Springer Study Edition [paperback, ISBN 0-387-97533-0]; 579 pp.

Cramer, W. A., and G. M. Soriano. 2002. Thermodynamics of Membrane Energy Transduction, in Energy Transduction in Membranes (W. A. Cramer, ed.); Educational Resources, Biophysical Society (http://www.biophysics.org/education/mechanisms.htm), 58 pp.

Cramer,W. A., and T. Kallas (eds.). 2016. Cytochrome Complexes: Evolution, Structures, Energy Transduction, and Signaling ; pp. 784; vol. 41 in the Series "Advances in Photosynthesis and Respiration;" Series Eds. Govindjee & T. Sharkey (Springer, Dordrecht); ISSN 1572-0233; ISBN 978-94-017-7479-6; DOI 10.1007/978-94-017-7481-9.

B Annual Reviews

Plant Physiology (1977,1996), Biophysics/Biomolecular Structure (1995), Biochemistry (2006), Genetics (2012) - complete references listed below; the only author of 5 Annual Reviews in 4 different subjects.

C. Publications ( 301 , 5/3/2022)

[CP] conference proceedings; [IR] invited review; [BC], book chapter/book); full detailed list supplied upon request.

D. Outside Lecture-Seminar Invitations (131, 5/3/2022)

list supplied upon request.