DAVID SANDERS Associate Professor 765-494-6453 LILY 1-228 retrovir@purdue.edu Associated website(s): Lab Website , Markey Center for Structural Biology , Publications

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PROFESSIONAL FACULTY RESEARCH

(Molecular virology) Entry of retroviruses and other enveloped viruses into cells; mechanism of enzymatic phosphoryl transfer; scientific publication ethics and peer-review reform.

BIO

One of the main challenges in gene therapy research is the delivery of the genetic material to particular cells. Retroviruses are most commonly used as the vehicles for inserting genes into the cellular genome. We have designed a set of novel viruses that show great promise for gene therapy. The viruses consist of retrovirus or lentivirus proteins on the interior and the proteins of other viruses on the surface. These pseudotyped viruses have been made with surface glycoproteins from a family known as the alphaviruses and from the Ebola virus.

A major focus of investigation concerns the ethics of scientific publication and the reform of grant and journal-article peer review.

Education

B.S., Molecular Biophysics and Biochemistry, Yale College

Ph.D., Biochemistry, University of California, Berkeley, 1989

Awards

• Moses Passer Lecturer in Chemistry and Chemical Biology, 2019
• American Association of University Professors, National Council, 2018-
• Federation of American Societies for Experimental Biology Science Policy Committee, 2016-
• Haines Lecturer in Biochemistry - Wabash College - 2015
• Purdue University College of Science Team Award
• Outstanding Mentor, Siemens Westinghouse Competition in Math, Science, Technology
• American Cancer Society Research Scholar Award
• National Science Foundation CAREER Award

Other Activities

• US Defense Threat Reduction Symposium on Scientific Collaboration with former Soviet Union scientists, St. Petersburg/Novosibirsk, Russia, July 15, 2003.
• The Cooperative Biological Research Annual Review Symposium sponsored by the U.S. Defense Threat Reduction Agency, St. Petersburg, Russia, July 12-21, 2004. Participated in lab inspections at Novosibirsk and talks about scientific collaboration, St. Petersburg, and Novosibirsk, Russia, July 12-21, 2004.

Grant Review/Study Section

• American Institute of Biological Sciences (AIBS)
• NSF Molecular Biochemistry Review Panel
• Basic Biomedical Sciences Study Section for California HIV/AIDS Research Program
• NIH/NIAID Grant Review Panel, Partnerships for Biodefense Viral Pathogens
• Indiana CTSI Collaboration in Translational Research (CTR)
• EPA Science to Achieve Results (STAR) Fellowship Program Panel
• American Cancer Society Research Scholar and Postdoctoral Fellowships Review Panels