Schedule
Location:
Purdue University
Hall for Discovery and Learning Research
207 S. Martin Jischke Dr.
West Lafayette, IN 47907
Tuesday, October 29, 2024 - Day 1: Advancing Lowe Syndrome Research and Clinical Impact
| Time | Topic |
|---|---|
| 8:00 AM - 9:00 AM | Registration and Networking Breakfast |
| 9:00 AM - 9:15 AM |
Welcome and Symposium Introduction R. Claudio Aguilar and Robert Nussbaum |
| 9:15 AM - 9:45 AM |
Alpelisib and alterations in the actin cytoskeleton Jennifer Gallop (University of Cambridge, UK). |
| 9:45 AM - 10:15 AM |
Control of cell fate specification and physiological maturation in the human brain by the lipid phosphatase OCRL Raghu Padinjat (National Centre for Biological Sciences, Bangalore, India). |
| 10:15 AM - 10:45 AM |
Networking Break |
| 10:45 AM - 11:45 AM |
Keynote Address: A pipeline for drug repositioning in Lowe Syndrome Antonella DeMatteis (University of Naples “Federico II”, Italy). |
| 12:00 PM - 1:00 PM |
Lunch Break |
| 1:00 PM - 2:30 PM |
Panel Discussion: Translating Research into Clinical Practice Panel Discussion with Experts in Lowe Syndrome Treatment and Patient Care - Co-Chaired by Eileen Brewer (Baylor College of Medicine, USA) and Yang Sun (Stanford University, School of Medicine) |
| 2:30 PM - 2:45 PM |
Networking Break |
| 2:45 PM - 5:00 PM |
Workshop on Structural, Cell, Biological, and Genomic Approaches to Lowe Syndrome Organized by Graduate, Undergraduate students and Postdoctoral fellows |
| 5:00 PM - 6:00 PM |
Workshop ADVANCE with Chris Sahley |
| 6:00 - 8:00 PM |
Networking Reception |
Wednesday, October 30, 2024 - Day 2: Supporting LS Research and Increasing Disease Awareness
| Time | Topic |
|---|---|
| 8:00 AM - 9:00 AM | Registration and Networking Breakfast |
| 9:00 AM - 9:30 AM |
OCRL role in Lipid Droplet Dynamics and Mitochondrial Activity: Implications for the Progression to Chronic Kidney Disease in Lowe Syndrome Leopoldo Staiano (Telethon Institute of Genetics and Medicine, Naples, Italy) |
| 9:30 AM - 10:00 AM |
Lowe Syndrome: Molecular Basis for Personalized Treatment Approaches R. Claudio Aguilar (Purdue University, IN, USA) |
| 10:00 - 10:15 AM | Coffee Break |
| 10:15 AM - 11:00 AM |
Flash Talks from Abstracts |
| 11:00 PM - 12:30 PM |
Roundtable Discussion: Patient Families and Clinicians Discussion moderated by the Jeri Kubicki (President of LSA) featuring Lowe Syndrome patient families and clinicians |
| 12:30 PM - 1:00 PM |
Lunch Break |
| 1:00 PM - 2:00 PM |
Translational Strategies for Advancing Lowe Syndrome Research: A Collaborative Grant Development Session Organized by Thomas Sors and R. Claudio Aguilar |
| 2:00 PM - 2:15 PM |
Closing Remarks R. Claudio Aguilar and Robert Nussbaum |