Biography
PERISTERA PASCHOU
Professor
LILLY 1-225
Phone: 765-494-1601
Email: ppaschou@purdue.edu
Click here for link to full CV
Dr. Paschou is a Professor at the Department of Biological Sciences at Purdue University and Associate Dean at the Purdue College of Science. She also serves on the leadership team of the Purdue Institute of Integrative Neuroscience. In 2019 she was named Showalter Faculty Scholar receiving one of the highest honors at Purdue University, recognizing oustanding faculty who are on an accelerated path to academic distinction. Dr Paschou works at the intersection of Data Science and genomics research. She studies human genetic variation around the world aiming to understand the cause of neurological and neuropsychiatric disorders as well as the factors that have shaped human population structure. Dr Paschou obtained her PhD from the University of Athens in Greece. During her graduate studies she also trained at the University of Oxford Welcome Trust Centre for Human Genetics and the Pasteur Institute in Paris. She did her post-doctoral studies at Yale University where she also trained in Clinical Molecular Genetics, receiving certification by the American Board of Medical Genetics. She has held visiting positions at UCSF, UCLA and the National Institutes of Health. Dr Paschou has established and led multiple international collaborative consortia aiming to identify the genetic basis of neurodevelopmental disease through the analysis of large-scale datasets. She led the EU-funded European network for the Study of Tourette Syndrome with participation of 200 investigators from 23 countries. She has served as Chair of the European Society for the Study of Tourette Syndrome, and she is currently Co-Chair of the ENIGMA-Tourette Syndrome Working Group, bringing together clinicians, geneticists, neuroimaging experts and data scientists from around the world in order to understand brain structure and function in neuropsychiatric disease.
Links to selected press-releases about our work can be found here.
Research at the Paschou lab
Elucidating the genetic background of neurodevelopmental phenotypes. A major focus of the Paschou lab is understanding the genetics of Gilles de la Tourette Syndrome and associated disorders including autism, obsessive compulsive disorder and attention deficit hyperactivity disorder. Dr Paschou studies genomewide datasets and has a leading role in multiple large-scale collaborative efforts such as the EMTICS and TS-EUROTRAIN consortia. She is also a PI in the NINDS project aiming to carry out a mega-genomewide association study for Tourette Syndrome on more than 12,000 cases. As a member of the Psychiatric Genomics Consortium, she studies neurobiology that cuts across traditional diagnostic boundaries of childhood neurodevelopmental disorders.
Studying human genetic variation around the world. Dr Paschou investigates human evolution and the migration patterns of the human population across the globe and in particular population movements around the Mediterranean basin (GENOMAP.GR project). Interdisciplinarity is an important aspect of her work transfering algorithms and methodology from the fields of Computer Science and Applied Mathematics to population genetics and medical genetics. In an era of Big Data and the ability to mine the genome of hundreds of thousands of individuals, such approaches pave the way towards the direction of personalized medicine.
EDUCATION
2005 Diplomate of the American Board of Medical Genetics (August 2005) - Clinical Molecular Genetics Specialty. Yale University School of Medicine, Department of Genetics - Medical Genetics Training Program (2002-2005)
2002-2005 Postdoctoral Training, Yale University School of Medicine, Department of Genetics (Supervisor: Kenneth K. Kidd)
1999-2002 National University of Athens, PhD
1999-2000 University of Oxford, “Wellcome Trust Centre for Human Genetics” – Training Fellowship
POSITIONS
2021 Professor, Purdue University, Department of Biological Sciences
2021 Associate Dean for Graduate Education $ Strategic Initiatives, Purdue College of Science
2019 Associate Dean for Online and Graduate Education, College of Science, Purdue University
2016 Associate Professor, (tenured) Purdue University, Department of Biological Sciences
2015 Associate Professor of Population Genetics, (tenured) Democritus University of Thrace, Department of Molecular Biology and Genetics
2010-2015 Assistant Professor of Population Genetics, Democritus University of Thrace, Department of Molecular Biology and Genetics
2011 Adjunct Investigator, National Institute of Child Health and Human Development, Bethesda, USA
2005-2010 Lecturer in Population Genetics, Democritus University of Thrace, Department of Molecular Biology and Genetics
2007 Visiting Scientist, Center for Neurobehavioral Genetics, Medical School, University of California Los Angeles, USA
2006 Visiting Specialist, Institute for Human Genetics, University of California San Francisco, USA
2002-2005 Postdoctoral Fellow, Department of Genetics, Yale University School of Medicine, USA
1999-2002 Research Associate, National University of Athens - European Cooperation Project: “Diabetes Prediction and Prevention - DIPP DEMO Project”
Boards of scientific societies
2014-2017 Board Member European Society for the Study of Tourette Syndrome (ESSTS)
2011-2014 Chair of the European Society for the Study of Tourette Syndrome (ESSTS)
2011-2012 Treasurer of the Board of Directors - Hellenic Association for Medical Genetics
Editorial boards
2009-2014 Academic Editor - Journal of Medical Genetics
2011-today Review Editor - Frontiers in Evolutionary and Population Genetics
2012-today Academic Editor - PLOS ONE
2015 Editor – Frontiers Research Topic: The Neurobiology and Genetics of Gilles de la Tourette Syndrome
Honors
2019 Showalter Faculty Scholar
2015 Latsis Foundation – Award for 2015 Scientific Studies by Young Researchers
2014 ARISTEIA II – Excellence Career Award, co-funded by Greece and the European Union
2005 Hellenic Endocrine Society, 1st research grant award
PUBLICATIONS
Latest News
Greater Indiana Society for Neuroscience Annual Meeting
September 8, 2023
As Chair of the Greater Indiana Society for Neuroscience, Dr. Paschou hosted the annual meeting of the Society at Purdue on September 8, 2023.
Our genome-wide association study points to novel locus for Tourette Syndrome.
February 2, 2023
Our paper is now published in Biological Psychiatry.
ENIGMA-TS paper published
August 18, 2022
Our paper describing the goals of the ENIGMA-TS Working Group is now published.
Dr Paschou receives new NIMH R01 grant
March 3, 2022
With support from the NIMH, Dr Paschou will lead the "Tourette Syndrome Genetics and Neuroimaging International Collaborative Study".