RESEARCH TOPICS

Cancer

Metastasis mechanisms and novel anti-cancer therapeutics.

3A: Metastasis mechanisms

Highlights of epsins' role in cancer cell invasion

Epside overexpression induces migratory behavior in epithelial cells.

Coon BG, Burgner J, Camonis JH, Aguilar RC (2010). The Epsin Family of Endocytic Adaptors Promotes Fibrosarcoma Migration and Invasion. J. Biol. Chem. 285(43):33073-81.

Coon BG, Direnzo DM, Konieczny SF, Aguilar RC (2011). Epsins' novel role in cancer cell invasion. Communicative & Integrative Biology 4(1):95-7.

Madhivanan K, Cao L, Staiger CJ, Aguilar RC. Molecular Determinants of the endocytic protein epsin controlling its localization and function in cancer cell migration and invasion. BioRxiv 229195.

Purdue University Center for Cancer Research

Purdue University Institute for Drug Discovery

Purdue University Institute for Integrative Neuroscience

Purdue Institute of Inflammation, Immunology and Infectious Disease

Purdue University Center for Science of Information

PULSE