RESEARCH TOPICS
Function of the vesicle trafficking machinery
1B) New paradigms on cargo recognition and endocytic network assembly
CARGO RECOGNITION
Artificial neural network for the prediction of tyrosine-based sorting signal recognition by adaptor complexes. Mukherjee D, Hanna CB, Aguilar RC. J Biomed Biotechnol. 2012;2012:498031. doi: 10.1155/2012/498031.
Introduction to the analysis of the intracellular sorting information in protein sequences: from molecular biology to artificial neural networks. Aguilar RC. Methods Mol Biol. 2015;1260:1-16.
The Na+ pump Ena1 is a yeast Epsin-specific cargo requiring its ubiquitination/phosphorylation sites for internalization. Sen A, Hsieh WC, Hanna CB, Hsu CC, Pearson M 2nd, Tao WA, Aguilar RC. J Cell Sci. 2020 Jul 21:jcs.245415. doi: 10.1242/jcs.245415. 2013 Jun;22(6):755-61.