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Our TRAP paper is finally out: 

Molecular determinants of Neu5Ac binding to a tripartite ATP independent periplasmic (TRAP) transporter eLife 13:RP98158

https://doi.org/10.7554/eLife.98158.3

2025 begins with a bang.  See an article about our work in JBC titled 

"Novel insights in the field of chronic cough Drug Discovery"

https://www.linkedin.com/feed/update/urn:li:activity:7283053805221412864/

Full paper in

https://www.jbc.org/article/S0021-9258(24)02611-5/fulltext

 

 

Late Addition

Trung and Ahn welcomed a baby boy (Ryan) on May 11th 2024.  Welcome to the gang Ryan.

 

Happy Birthday Camille!

 

images/camille_bday.jpeg

 

Sept 2023,  Yiyang Cheng (Evelyn) joined the lab as a graduate student. 

 

July 14 - Congratulations to Vijayan.  

Ramya and Vijayan have a new baby Tara.

 

June  2023:  We now have a lab web-page

Check out our latest paper.

Variability in phenylalanine side chain conformations facilitates broad substrate tolerance of fatty acid binding in cockroach milk proteins.  

by Partha, Vijayan, and others. 

https://doi.org/10.1371/journal.pone.0280009


 

RamS Lab

The laboratory has a long-term interest in understanding the relationship between atomic resolution structures and molecular function. We use X-ray crystallography and electron cryo-microscopy as the primary structure determination tools. We are interested in a wide variety of enzymes and membrane transporters, from both a basic biology perspective as well in their relevance to disease and applications.